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metronidazole will raise the amount or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.butabarbital will lessen the extent or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.Keep away from coadministration of sensitive CYP3A4 substrates with